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Lehmann R, Zhao X, Weigert C, Simon P, Fehrenbach E, Fritsche J, et al
The initial dose is 25 mg daily, which can be increased up to a maximum of 200 mg as prescribed
Key safety observations from available trial data include: Elevated resting heart rate in a dose-dependent manner Gastrointestinal adverse effects (nausea, vomiting, diarrhoea) as the most common side effects, consistent with the GLP-1 receptor agonist class [1] [3] No clinically significant QT interval prolongation was reported in available data, though the extent of formal thorough QT assessment has not been fully detailed in published sources
And with more GLP-1s expected to enter the market soon, there will be downward price pressure over the next few years