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Evidencia citada Meta-anlisis de 3 ECA (878 sujetos): 14.33% de peso corporal vs placebo, con reduccin de IMC, cintura, glucosa en ayunas, HbA1c y presin arterial, sin diferencia significativa en eventos adversos

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Moreover, the amount of time that the effects of a vitamin B12 injection will last depends on several factors

One trial demonstrated that GLP-1 therapy plus exercise preserved bone mineral density while GLP-1 therapy alone decreased it

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While this provides a substantial sample, the patient population may not fully represent the entire Polish population, potentially reflecting individuals with higher socioeconomic status, greater medication affordability, different health literacy levels, or better geographic access to private clinics