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The laser beam profile was approximated to follow a 3D Gaussian distribution, measurement reads were binned at 20 s, appropriate for fluorescent species in solution, and the first order correction was calculated daily following calibration with 20 nM Rhodamine 6 G
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The only current exceptions are Rybelsus , an oral pill for type 2 diabetes, and, recently in 2026, Wegovy the first oral GLP-1 drug available for weight loss
Kitada et al., 2020
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The evolution of GLP-1 receptor agonists from diabetes drugs to breakthrough weight-loss therapies [1:45]
