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Common side effects of topiramate include: Burning, numbness, or tingling in your feet, hands, face, or mouth (paresthesia) Dry mouth or altered taste Constipation, nausea, or stomach pain Dizziness, drowsiness, or slowed reactions Nervousness Headache Shaking or muscle weakness Nosebleeds Involuntary eye movements Menstrual irregularities Avoid alcohol and other central nervous system (CNS) depressants, such as sedatives and certain pain medications, as they can increase these side effects

J Cell Biol 113: 13311340 CummingsBS,AngelesR,McCauleyRB,LashLH (2000) Role of voltagedependent anion channels in glutathione transport into yeast mitochondria

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DSIP modulates the natural architecture of sleep by promoting delta waves without suppressing REM sleep