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Alleviation of Depression by glucagon-like peptide 1 Through the regulation of neuroinflammation, neurotransmitters, neurogenesis, and synaptic function
Other mechanisms explaining the effects of metformin on thyroid cell growth and viability are the downregulation of cyclin D1, the increase of the ER stress and the reduction of mRNA levels of AKT, PI3K, and FOXO1 LRP2 and p-JNK, genes that play a crucial role in cell proliferation and survival (Oyadomari and Mori, 2004
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International journal of molecular sciences , 15 (3), 48374855