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The active region of TB-500 (the LKKTETQ sequence) binds G-actin monomers, preventing their polymerization into filamentous F-actin

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In practical terms, nerve cells may have a harder time meeting the demands of everyday movement, balance, and sensation

Therefore, in our transcriptomic analysis, special interests were paid to pathways of carbon metabolism, lipid metabolism (glycerophospholipid) and DNA biosynthesis (including cell cycle, DNA replication and purine/pyrimidine metabolism)