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Here are two of the most notable experiments to date: In an 11-day study, obese mice treated with 20mg/kg of 5-amino-1MQ trice daily experienced a 5.1% weight reduction from baseline, while control mice gained 1.4% in body weight

The NIH Vitamin B12 Fact Sheet for Health Professionals notes that oral supplementation is appropriate for many patients who do not have intrinsic factor deficiency

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I use this along with tirzepeptide, and it has helped maintain my weight and a boost of energy