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Chronic treatment with high concentrations of liraglutide (200 and 400 g/kg) and KBP-089 (2.5 g/kg) resulted in a 7 and 15% vehicle-corrected body weight loss, respectively, while the combinations (L 200 g/kg + KBP 2.5 g/kg and L 400 g/kg + KBP 2.5 g/kg) resulted in a 17 and 21% weight reduction, respectively (Fig

The approved doses in China are 4 mg and 6 mg for weight management, with a 9 mg dose under review for moderate-to-severe obesity

Multi-strain Lactobacillus + Bifidobacterium outperformed single strains for stool consistency and microbiota modulation

Regarding the comparative safety profiles of GLP-1 receptor agonists vs aspirin, acute kidney injury occurred in 1.15% of patients taking GLP-1 receptor agonists compared with 2.8% of those taking aspirin (HR, 0.369