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The filter was washed two times with 100 L of UA, centrifuged at 14,000 g for 15 min, and incubated with 100 L of IAA solution (0.05 M iodoacetamide in UA) for 20 min in the dark
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Lastly, downstream products of KYN exert excitotoxic effects that can trigger apoptosis through activation of ionotropic glutamate receptors impacting neuroplasticity
Sources: Glutathione: a key player in autoimmunity American Diabetes Association Diabetes Care Glutathione Synthesis Is Diminished in Patients with Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine
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Hepatol Res 2008;38 Suppl 1:S3-8
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