[1] [4] Animal studies have shown excretion into milk, but human data remains absent
Kirkegrd, J., Mortensen, F
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PMID 2185014
The Potential Mechanisms of the GLP-1 Effects on Bone Metabolism The continuous cycle of bone formation and bone resorption in osseous tissue maintains normal bone quality and bone mass
The total human evidence base, as of this writing, consists of the following: 1) a Phase I safety trial of 42 healthy volunteers that was registered in 2015, canceled in 2016, and never published, 2) a retrospective case series of 12 patients with knee pain, no control group, and no validated outcome measure, and 3) a 2025 pilot safety study involving two healthy adults who received intravenous infusions at a single private clinic in Florida