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This regulatory status reflects the absence of completed human clinical trials establishing safety and efficacy to approval standards

108, 118 This is not surprising, given that the species-specific diet in mice is very different from humans who are omnivores and during much of their evolution consumed low-glycemic load diets

In laboratory studies, TB-500 has been evaluated for its interaction with actin-binding pathways, cytoskeletal organization, and cellular migration processes

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The time required for each rabbit to regain normal ambulation, without signs of lameness, was recorded