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The peptides reduction of excitotoxicity and oxidative stress, enhanced neurotrophic factor expression, and improved blood flow all contribute to nerve recovery potential

While Semaglutide (Ozempic, Wegovy) targets one receptor and Tirzepatide (Mounjaro, Zepbound) targets two, Retatrutide activates three distinct metabolic receptors simultaneously

Food would create a physical barrier, diluting the peptide and preventing this direct contact

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The dorsal putamen was selected as the center of the volume of interest due to its relatively homogenous mix of neurons and astrocytes, and suitable distance from bone and other regions that could compromise signal quality