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Biopsy-proven NASH : Patients with histologically confirmed NASH, particularly those with significant inflammation or early fibrosis (F1-F2), may be considered for off-label GLP-1 therapy, especially if they have failed lifestyle modification or have contraindications to other therapies like vitamin E or pioglitazone

& Cui, Y

The useful observation in this window is simple tolerability whether the chosen route is comfortable and consistent

92:1061-1085 [PMC free article] [PubMed] 67

Several medications can potentially cause heavier periods, including blood thinners, some anti-inflammatory drugs, and certain hormonal medications

In rodent models, peripheral administration of exendin-4 (EX4), a GLP-1RA has been shown to reduce motivation for sucrose, as evidenced by decreased responding in progressive ratio operant-conditioning tasks (Dickson et al., 2012)