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Retatrutide additionally shows a dose-dependent increase in heart rate, attributed to its glucagon-receptor activity, and indirect network meta-analyses flag the highest adverse-event burden among the modern agents for the most potent drugs

Int J Mol Sci 23(4):2110

GLP-1 therapies slow down the process of food digestion and increase feelings of fullness, leading to a reduction in food intake

More serious, though rarer, side effects include pancreatitis (inflammation of the pancreas) and potential thyroid problems

The research is ongoing to explore other potential uses of semaglutide

And the broader semaglutide refrigerator storage guide covers both compounded and brand-name products