Take-home message: - Peptides and assorted experimental drugs, like TB-500 and MK-677, are being recommended by fitness influencers to grow bigger muscles, lose fat, and recover from injuries faster - These drugs, many of which are claimed to boost levels of growth hormone, were studied in rodents and very small groups of human volunteers before being abandoned for not being beneficial or for causing unacceptable side effects - They are banned by the World Anti-Doping Agency and appear to be illegal in Canada and the United States, but can be purchased online
Iron ion and MDA levels in the cardiac tissue of TAC-operated mice were significantly increased, while PQQ treatment reversed these changes (Figures 2B,C)
When injected directly into the bloodstream, it can potentially aid in improving metabolic rates, leading to increased energy production and, over time, weight reduction
Other small studies suggest it helps reduce inflammatory cytokines in the gut lining
We chat about our own experiences with this idea, how we've both navigated those thoughts in our careers, and how Kylee works with clients to address body image issues so they can fuel better and thrive
Pancreatitis can also be diagnosed by biopsy during surgical exploration, though there is controversy as to whether removing a piece of the pancreas generates additional inflammation