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Of those 15 cases, 12 were found to be possibly linked to use of GLP-1 RAs, while 3 could not be assessed due to missing clinical information

The two most common were the Pittsburgh Sleep Quality Index (PSQI) and the Leeds Sleep Evaluation Questionnaire (LSEQ)

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We do not recommend B12 injections while pregnant or breastfeeding

Tolerability and access, however, remain significant considerations

Tirzepatide, a dual GIP and GLP-1 receptor agonist approved for type 2 diabetes and chronic weight management, commonly causes gastrointestinal effects including nausea, diarrhea, and constipation