doi:10.1016/S0140-6736(21)00845-X
We conducted searches using the following search terms: cisplatin, cancer, cisplatin nephrotoxicity, acute kidney injury, cisplatin-induced AKI, autophagy, AMPK-mTOR-mediated autophagy, necroptosis, RIPK1/RIPK3/MLKL-mediated necroptosis, necroinflammation, nephroprotective, autophagy activators, and necroptosis inhibitors
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Pesquisadores de laboratrio tambm dependem da GSH como um componente crtico em meios de cultura celular para regular as condies redox, permitindo o estudo preciso do estresse oxidativo, do metabolismo de frmacos e das vias de sinalizao celular
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