The clinical explanation is not that willpower has failed
These include people with type 2 diabetes or higher blood sugar, people with a history of cancer, and people with eye conditions like diabetic retinopathy
Transl Neurodegener 11:43
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Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults
These multidimensional factors spanning mitochondrial metabolism, cellular aging, metabolic function, and childhood trauma provided more detailed signatures to predict longitudinal changes in depression severity than each individual factor alone