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Hypertension, smoking status, previous stroke and renal function were tested as potential confounders but were excluded in the final model as they did not affect the OR significantly

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A second study investigated delivery of GLP-1 in a SOD1 G93A mouse model using an intracerebroventricular injection of mesenchymal stem cells (MSC) stably transfected to secrete GLP-1 21

Expected Results and Timeline Understanding realistic outcomes and timeframes helps set appropriate expectations for GLP-1 therapy