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The results indicate that 1,3-Dioxolane, 4-ethyl-5-octyl-2,2-bis(trifluoromethyl)-, trans- exhibited the lowest toxicity, classified as Class 5 in oral administration, suggesting it is relatively non-toxic
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To investigate whether this partial effect was due to an incomplete knockdown, we performed experiments in HEK293 cells with both -arrestin isoforms deleted by CRISPR-Cas9 41