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Regarding apoptosis, pretreatment with 20 nmol/l Ex-4 protects cardiac progenitor cells from palmitate induced cell death, and this protective effect extends even under hypoxic conditions but could be reversed by the GLP-1-R-Antagonist Exendin(9-36)

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3.2.5 Extracellular vesicles and exosomes Mesenchymal stem cells (MSCs) have been investigated for their role in organ protection in sepsis and acute respiratory distress syndrome (ARDS), primarily due to their ability to secrete beneficial exosomes that can transfer mitochondria or mitochondrial components to other cells (142)