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Good reporting practice Record enzyme source, substrate concentrations, SAM concentration, buffer, temperature, readout method, and salt-equivalent concentration whenever potency is compared

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The term impaired sensitivity to B12 more aptly captures this condition than functional B12 deficiency, encompassing a broader portrayal of the potential underlying pathological physiological process involving decreased responsiveness to B12 treatment, including B12 absorption, transport, intracellular metabolism, and mitochondrial MMA metabolism

When in compliance with federal law, compounded drugs are not subject to FDA approval and do not have to undergo safety, effectiveness, or manufacturing review

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