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GLP-1 medications can produce substantial caloric restriction through appetite suppression and early satiety, leading to weight loss that may exceed 15-20% of body weight over several months with higher doses of semaglutide 2.4 mg or tirzepatide

BMC Cancer 2022 Jul 2;22(1):724

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DOI: 10.1089/ars.2010.3586 67

The compound is commonly investigated in biochemical research for its interaction with NNMT-related metabolic processes and molecular signalling mechanisms

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