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By constantly signaling to the brain that the body is full, peristalsis (rippling GI waves that push contents through the gut) is slowed, thereby disrupting the bodys natural digestion process. According to Fereday: The anecdotes of the early adopters are not necessarily that representative of how things will play out if this class of drugs goes mainstream
Findings also suggest that GLP-1RA therapy was associated with significantly lower risks of high blood pressure emergency and hospitalization
Frontiers in neuroscience 12:739
Yet the Lipovia patch claims to deliver GLP-1 effects transdermally through nanotechnology. Scientifically, thats impossible with current technology
Both peptides appear to require indefinite use for sustained weight maintenance, similar to how blood pressure medications require ongoing use to maintain effect
For most GLP-1 medications the injection process remains similar
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