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Sterile water lacks preservatives, meaning each needle puncture increases contamination risk

PMID 15010535

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But some might feel pain at the injection site, mild diarrhea, or itching

KEAP1 protein has also been shown to co-localise with intracellular inclusions in MNs of postmortem ALS spinal cord [245], possibly through an interaction with p62 observed in several ALS inclusions [246]