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Emerging evidence further suggests that SFN may interfere with Hedgehog signaling through modulation of Gli transcription factor function, though the precise mechanisms require additional validation (74)

2003 Dec;2(12):1361-8

10.1515/hmbci-2015-0073 47 BowmanR

Rapamycin, an inhibitor of mammalian target of rapamycin (mTOR) complex 1, exhibits cardioprotective effects in ferroptotic cells, where mTOR overexpression protects against iron-overload-induced cell death, a process exacerbated by mTOR deficiency (67, 68)

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