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(Het schema staat onderaan de pagina.) Uit glutaminezuur en cystene wordt -glutamylcystene gemaakt via het enzym glutamaatcysteneligase (GCL, ook -glutamylcystenesynthetase)

In a randomized, controlled clinical study (Study F), in adult patients with type 2 diabetes not using oral antidiabetic medications (n = 518), a basal-bolus regimen of insulin glargine once daily at bedtime or NPH insulin administered once or twice daily was evaluated for 28 weeks

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