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In this review, we discuss the pipeline of obesity pharmacotherapies with focus on entero-pancreatic hormone-based molecules, and we evaluate the data from early and late phase clinical trials on their safety and efficacy on WL in people with and without T2D

Costly new generation weight loss drugs are unaffordable for most people, which has opened up a black market for cheaper, unregistered and untested versions of the medicines being sold across the country, posing a public health threat, as highlighted by a newspaper expos and unpacked by Bhekisisa health journalists

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doi: 10.1016/j.cmet.2021.01.015 45 FenselauHCampbellJNVerstegenAMMadaraJCXuJShahBPet al

Although both use lithium-based technology, their designs are different, which affects their discharge characteristics