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Suppression of food intake by Glp1r/Lepr- coexpressing neurons prevents obesity in mouse models

Polyunsaturated fatty acid suppression of hepatic fatty acid synthase and S14 gene expression does not require peroxisome proliferator-activated receptor alpha

A proportion of infants and children with sepsis progress to cardiac failure as part of multiple system organ failure (hepatic, renal, cardiac, pulmonary) [100]

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This is why the ENDO research found that greater muscle loss correlated with less improvement in HbA1c

6C, D), suggesting that, at least in the initial phase of treatment, these compounds drive their weight-lowering effects mostly by reducing food consumption, without inducing thermogenic responses