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Suzuki S, Sakurai D, Sakurai T, Yonekura S, Iinuma T, Okuma Y, et al

The mechanism involves upregulation of tissue inhibitors of metalloproteinases (TIMPs) and simultaneous downregulation of matrix metalloproteinases (MMPs), shifting the extracellular matrix balance toward net deposition rather than degradation

This impairment increases as the BAC level rises, which is why it's essential to avoid activities like driving when consuming alcohol

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These characteristics make the WKY rat an important model for understanding the pathophysiological mechanisms of depression and its treatment

Sonnenburg JL, Xu J, Leip DD et al (2005) Glycan foraging in vivo by an intestine-adapted bacterial symbiont