Thymosin Beta-4 Modulates Cardiac Remodeling by Regulating ROCK1 Expression in Adult Mammals, Maar K, Thatcher JE, Karpov E, Rendeki S, Gallyas F Jr, Bock-Marquette I, International Journal of Molecular Sciences, International Journal of Molecular Sciences, 2025;26(9):4131
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Furthermore, in signaling studies that used cell lines with recombinantly expressed human GIPR or GLP-1R, tirzepatide stimulated cyclic adenosine monophosphate (cAMP) accumulation by either receptor with potency similar to that of native GIP and approximately 13-fold weaker than that of native GLP-1 [1]