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An a priori sample size calculation was performed using repeated measures, within factor ANOVA
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Energy and mood improvements may follow
No pattern of serious adverse events has been observed in the human studies completed to date
Those with kidney disease or other health conditions may need personalised advice from a dietitian
Assessment of the effect of food on PF-06882961 administration revealed similar exposure (as measured by AUC inf ) and t 1/2 when administered in the fed state, compared with the fasted state (Table S11), indicating that PF-06882961 can be dosed in both the fed and fasted states
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