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Finally, an imbalance in GSSG:GSH ratio induced ER stress and dependency on the ER-associated degradation pathway, driven by a shift in protein disulfide isomerases towards their oxidized forms

By selectively recruiting LXR coregulators, GF2 reduces hepatic lipid accumulation and suppresses inflammation of identify GF2 as a promising therapeutic candidate for metabolic liver diseases (8587)

Intriguingly, in the animal nervous system, GSH has been identified as a neuromodulator/neurotransmitter 34,35,36 , suggesting a potential conceptual parallel in GSH-mediated signal transmission across different kingdoms of life

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