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Common causes include liver disease (which releases stored B12), kidney disease (reducing B12 clearance), haematological malignancies, solid tumours, and excessive supplementation

As anticipated, the ANOVA significant DIA sites were mainly upregulated in HeLa cells after 10 min EGF stimulation with an average log2 fold-change of 1.0 and belonging to the clusters B, C, and D of intermediate stimulators, late stimulators, and terminal effectors defined in the HeLa dataset 2

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FUNGI 16: 14-15

Athanasiou A, Clarke AB, Turner WE, Kumaran NM, Vakilpour S, Smith PA, et al

What we'll tell you is that 0.10% is a research-informed, deliberately conservative, fully disclosed concentration chosen to sit in the studied, well-tolerated range for a signaling peptide rather than to win a spec-sheet contest