Bismuth Subsalicylate and Hydrogen-Sulfide Release
15 While the study showed a lower risk of sight-threatening retinopathy with SGLT2i, there was no increased risk with GLP-1 RAs compared with DPP-4i or sulfonylureas
Management includes maintaining adequate hydration (1.52 litres daily), rising slowly from sitting or lying positions, and taking small frequent meals
More recently, tirzepatide, which targets both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors, has received approval for treating type 2 diabetes and/or obesity
Storage Store at -20C, protect from light
Low blood sugar may occur if these weight management medications are taken in addition to glucose-lowering drugs that can cause hypoglycemia (eg, insulin or a sulfonylurea)