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10.1038/s41467-018-04422-2 90 LuretteO.Martn-JimnezR.KhanM.ShetaR.JeanS.SchofieldM.et al (2023)

Losing primarily fat while preserving lean muscle mass produces far better outcomes than losing a proportional mix of both

reported significant improvement in plaque size and penile curvature in patients using daily vitamin E and colchicine compared to ibuprofen alone (16)

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Glutathione S-transferase in research-subject organs

-Tocopherol is rapidly lost from the circulation, and more metabolites of -tocopherol are excreted in urine compared to -tocopherol, suggesting less -tocopherol is needed for use by the body (1)