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6a,b and Extended Data Fig
#almatherapeutics "Consider tolerability, adherence, comorbidities, access, and long-term strategy" Love these as focus areas
Some portion of intranasally administered peptides may reach the central nervous system through the olfactory pathway, bypassing the blood-brain barrier
Step 1: Identify your primary goal
The execution of pyroptosis, mechanistically, relies on gasdermin protein family members (160)
Sterile saline or other buffers may also serve as reconstitution solutions depending on the compound
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