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GLP-1 is a 30-amino acid peptide hormone produced by differential post-translational processing of the proglucagon precursor protein by prohormone convertase 1/3 (PCSK1) in intestinal L-cells and in neurons of the nucleus tractus solitarii (NTS) in the brainstem
Rybelsus and Ozempic: Whats the Difference
Patients with low-sensitivity variants may require higher doses to achieve the same appetite suppression as others, while high-sensitivity individuals might experience strong effects at lower doses
doi: 10.3389/fphar.2022.857869 130 LiWTanMWangHWangZPangYYangRet al
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