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B12 deficiency elevates homocysteine, a sulfur-containing amino acid that damages arterial endothelium and increases atherosclerosis risk
4 Rates were lower in TRANSCEND-T2D-1: 5.1% at 12 mg, 4.5% at 9 mg, and 2.2% at 4 mg
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This is in line with what has been seen with other GLP-1 RAs [45]
The medication is available in both brand-name and compounded forms, although the compounded forms are not FDA approved
"Both medications are excellent options for managing type 2 diabetes, but the choice between tirzepatide and semaglutide will depend on the patient's specific needs, weight management goals, and response to other therapies," says Candice Sapp, RD
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