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Handbook of Clinical Neurology, 156, 431443
Month 5 (Weeks 17 through 20): 12.5mg weekly Few patients need to go this high, but for those with higher body weights or slower metabolic responses, 12.5mg can provide additional benefit
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This dual action: Enhances insulin sensitivity beyond GLP-1 alone Promotes more substantial appetite suppression Improves metabolic function through multiple pathways May lead to greater fat loss, particularly visceral fat Think of it as addressing weight loss from two complementary angles rather than one
Patients with hypothyroidism frequently experience weight gain, fatigue, and difficulty losing weight even with dietary modifications and exercise
In clinical trials, some patients saw an approximate weight reduction of 9-17% after 68 weeks of consistent weekly injections
