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Symptoms typically peaked during dose escalation and tapered during maintenance

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At PRIME Medicine, we help patients create personalized strategies designed to support long-term weight stability, not just short-term weight loss

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When to Seek Medical Advice About Menstrual Changes Consult your GP if periods stop for three or more months, bleeding becomes unusually heavy, or you experience intermenstrual spotting

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How to check for Vitamin B12 deficiency with lab tests: Serum Vitamin B12 levels: should be in the top 75% percentile of the lab reference range (yes even mid-range can still be too low)

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If you miss a dose by fewer than 3 days, take it as soon as you remember and resume your regular schedule the following week

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The body excretes excess B12 through the kidneys, and no Tolerable Upper Intake Level exists because B12 toxicity from dietary sources is extremely rare

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