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It's important to note that endogenous GLP-1 is rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4), giving it a very short half-life in circulation

Erythrocyte NADPH oxidase activity modulated by Rac GTPases, PKC, and plasma cytokines contributes to oxidative stress in sickle cell disease

GPX1 is a tetramer that can react with H 2 O 2 and soluble low-molecular hydroperoxides, but not with more complex lipid hydroperoxides

For the peptides direct action, no

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