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Compounded medications are not reviewed or approved by the FDA in the same way as FDA-approved drug products

Glutathione is one of the most active thiol compound acting as a reducing agent and it reacts with the disulfide bonds in wheat proteins, thus restricting the disulphide mediated polymerization of gluten proteins in dough

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Therefore, noting the lack of spontaneous oxidation of free GSH between the two EDTA-treated samples stored at 80 o C, this result also suggests that the differences in GSH between the heparinized plasma (Preparation Condition 1) and deproteinized EDTA-treated plasma (Preparation Condition 2) are due to spontaneous oxidation of free GSH occurring in the heparinized plasma prior to the deproteinization process

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