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This physiological response helps prevent hypoglycaemia, a significant advantage over some other diabetes treatments

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Regardless of the precise mechanisms contributing to this phenomenon, a growing appreciation is that the central nervous system (CNS) is sensing multiple changes in redundant hormonal systems that drive hyperphagia to restore a previous body weight set point 54

doi: 10.1016/j.biomaterials.2025.123126 10 ZhouQWuHMiaoFChenLWangYZhangXet al

Recent investigations have shifted predominantly toward topical delivery systems, reflecting ongoing challenges with oral curcumin bioavailability despite enhancement strategies