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Whilst some probiotic strains may theoretically influence endogenous GLP-1 secretion through metabolite production, there is no established evidence that supplements achieve clinically meaningful increases in circulating GLP-1 levels
To minimise problems: Sip water regularly and aim for around 2 to 3 litres per day, unless your doctor advises otherwise Consider water rich foods such as soups, cucumbers and watermelon Start with smaller meals, eating slowly and stopping at the first sign of comfortable fullness Focus on softer, easy to digest foods if you feel unwell 4
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Similarly, the Cardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection Fraction study focuses on obese patients with HFpEF to evaluate improvements in cardiac structure, exercise tolerance, and metabolic health [64]
Always consult your prescriber before making changes to any medication.
Charubin K, Bennett RK, Fast AG, Papoutsakis ET
