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Most people can expect to see results within 12 weeks of starting treatment

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L-carnitine can improve exercise tolerance in patients with diseases, such as indicators like exercise time, maximal oxygen uptake, and lactate threshold

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A pilot trial of melatonin in 22 breast cancer patients receiving paclitaxel- or docetaxel-based chemotherapy reported that 21 mg of daily melatonin appeared to reduce CIPN incidence (45%) and severity compared to historical controls (~60%) without impacting quality of life (Nahleh 2010)

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Also in 2002, a GIP analogue with an N-terminal substitution of glutamic acid in position 3 with proline (Pro3), was made as an attempt to prolong the GIP actions by protecting from DPP-4 degradation (66) ( Figure 1 )

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