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Results Airway epithelial cells export GSH in response to CSE over time Bronchial epithelial cells were exposed to CSE for 12, 24, and 48 hours to determine whether cells retain or export GSH in response to the CSE exposure
POP-NP administration restores this regulatory axis by competitively binding miR-410-3p, relieving Nrf2 inhibition, enhancing HO-1 expression, and normalizing renal injury markers (e.g., serum creatinine, BUN)
As controls for the synergistic combination of ceftazidime/avibactam (AVI/CAZ), each component was also used at the lower concentration present in the combination as well as higher concentrations that individually inhibited 2030% of growth
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Intracellularly, mainly in adipose tissue, its antioxidant action is limited, thus uric acid could interact with other radicals, and this could initiate a cascade of reactions to generate superoxide forms