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They tried a few tricks: DPP-4-resistant versions: tweaking the GLP-1 molecule so DPP-4 cant see where to cut it Fatty acid tails: causing the GLP-1 to latch onto albumin in your blood, hiding from DPP-4 Encapsulation: wrapping the molecule in protective coatings so it survives longer before being exposed to enzymes These hacks meant the drug could hang out in the bloodstream for hours, or even days, instead of minutes

These sequences are like a language known as the Genetic Code, which is a part of our genes

RNA Biol

With respect to sex, the hazard ratio was lower among men (0.74, 95% CI 0.54 to 1.01) than women (1.10, 0.82 to 1.48), but with overlapping confidence intervals

The Diabetes Control and Complications Trial Research Group

doi:10.1007/s00114-016-1362-3