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it only increases the likelihood of severe side effects that could force you to stop treatment altogether

They found that capsiate suppressed the production of HIF-1 and activated SLC2A1, thereby diminishing ferroptosis and alleviating OA in murine models [106]

PubMed Central

AMPK activation can enhance the expression of genes associated with antioxidant defense mechanisms (Joo et al., 2016)

While most of these benefits still go back to its role as an antioxidant, the targeted benefits go much further than what we once thought