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In dermal wound trials, TB4 has been explored for accelerating re-epithelialization, and is under investigation in ocular injury models (e.g., corneal wound healing)

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In its copper-bound form, the peptide exhibits biological activity that the free apopeptide (GHK without copper) largely cannot replicate, noting that the copper ion is critical for the compounds regenerative and redox-active properties

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Moreover, 6147 BRCA-related targets were acquired from GeneCards and OMIM databases